منابع مشابه
Pivotal role of choline metabolites in remyelination.
Neuroprotective approaches for central nervous system regeneration have not been successful in clinical practice so far and compounds that enhance remyelination are still not available for patients with multiple sclerosis. The objective of this study was to determine potential regenerative effects of the substance cytidine-5'-diphospho (CDP)-choline in two different murine animal models of mult...
متن کاملHigh-performance liquid chromatography of water-soluble choline metabolites.
We have developed a new method for the separation of [3H]choline metabolites by high-performance liquid chromatography. Using this method it is possible to separate, in one step, all of the known major water-soluble choline metabolites present in crude acid extracts of cells that have been incubated with [3H]choline, with baseline or near-baseline resolution. We use a gradient HPLC system with ...
متن کاملEffect of rumen-protected choline on performance, blood metabolites, and hepatic triacylglycerols of periparturient dairy cattle.
The effects of a dietary supplement of rumen-protected choline on feed intake, milk yield, milk composition, blood metabolites, and hepatic triacylglycerol were evaluated in periparturient dairy cows. Thirty-eight multiparous cows were blocked into 19 pairs and then randomly allocated to either one of 2 treatments. The treatments were supplementation either with or without (control) rumen-prote...
متن کاملProton NMR of (15)N-choline metabolites enhanced by dynamic nuclear polarization.
Chemical shifts of protons can report on metabolic transformations such as the conversion of choline to phosphocholine. To follow such processes in vivo, magnetization can be enhanced by dynamic nuclear polarization (DNP). We have hyperpolarized in this manner nitrogen-15 spins in (15)N-labeled choline up to 3.3% by irradiating the 94 GHz electron spin resonance of admixed TEMPO nitroxide radic...
متن کاملEffects of ruminally protected choline and dietary fat on performance and blood metabolites of finishing heifers.
A 120-d finishing study utilizing 318 heifers (342 kg initial BW) was conducted to examine effects of ruminally protected choline (RPC) in diets containing graded concentrations of tallow. Heifers were blocked according to previous nutrition (full-fed or limit-fed) and allotted to 24 pens containing 11 to 15 heifers. Two pens, one within each block, were assigned to each of 12 factorially arran...
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ژورنال
عنوان ژورنال: Current Opinion in Lipidology
سال: 2016
ISSN: 0957-9672
DOI: 10.1097/mol.0000000000000259